Buy Verapamil

Verapamil and its Uses
Verapamil belongs to a class of medications called calcium channel blockers.

Verapamil is used to treat irregular heartbeats (arrhythmias) and high blood pressure. Verapamil relaxes your blood vessels so your heart does not have to pump as hard. Verapamil also increases the supply of blood and oxygen to the heart to control chest pain (angina). If taken regularly, Verapamil controls chest pain, but it does not stop chest pain once it starts.

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Working Mechanism of Verapamil
Verapamil blocks the transport of calcium into the smooth muscle cells lining the coronary arteries and other arteries of the body. Since calcium is important in muscle contraction, blocking calcium transport relaxes artery muscles and dilates coronary arteries and other arteries of the body. By relaxing coronary arteries, verapamil is useful in treating and preventing chest pain (angina) resulting from coronary artery spasm. Relaxing the muscles lining the arteries of the rest of the body lowers blood pressure, which reduces the burden on the heart as it pumps blood to the body. Reducing heart burden lessens the heart muscle's demand for oxygen, and further helps to prevent angina in patients with coronary artery disease.

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Verapamil Dose
Missed Dose

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of Verapamil.

Excess Dose of Verapamil

Verapamil in excess dose may show symptoms such as dizziness, weakness, chest pain, shortness of breath, fainting, an unusually fast or slow heartbeat, coma, slurred speech, and confusion.

Conditions for Storage of Verapamil

Store Verapamil at room temperature away from moisture and heat.

Verapamil Tablets: Verapamil 80 mg, Verapamil SR 120 mg, Verapamil SR 180 mg

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Food and Drug Interactions with Verapamil

• The blood levels of alcohol may be increased by Verapamil. This can increase the effects of alcohol and cause blood pressure to drop.
• Verapamil increases the effect of medicines used to lower blood pressure.
• When first taken with other blood pressure lowering medication it may cause a large drop in blood pressure and therefore dizziness.
• Verapamil may increase the risk of the heart slowing and heart block.
• The risk of heart failure and severe drop in blood pressure is increased if Verapamil is taken with beta-blockers.
• Rifampicin increases the removal of Verapamil from the body, making it less effective.
• Phenobarbital and phenytoin reduce the blood levels of Verapamil.
• Verapamil significantly increases the blood levels of digoxin to harmful levels. The dose of digoxin must be reduced if these two medicines are used together.
• Verapamil increases the blood levels and therefore the effects of cyclosporin, carbamazepine, theophylline and quinidine.

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Contraindications with Verapamil
Verapamil is contraindicated in the following:

• A problem common in the elderly, related to poor control of the working of the heart (sick sinus syndrome)
• Defect of the heart's electrical message pathways resulting in decreased function of the heart (heart block)
• Failure of the heart to maintain adequate circulation of blood (cardiogenic shock)
• Heart failure
• Irregular heart beats (arrhythmias)
• Life long inherited blood diseases which can cause a variety of symptoms, including mental health problems (porphyrias)
• Low blood pressure (hypotension)
• Slow heart rate of less than 50 beats per minute (bradycardia)
• Allergy to one or any of its ingredients
• Pregnancy and Breast-feeding

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Precautions with Verapamil
Verapamil should be used with caution in:

• Children
• Defect of the heart's electrical message pathways resulting in decreased function of the heart (heart block)
• Heart attack (myocardial infarction)
• Liver disease

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Adverse effects with Verapamil
The adverse effects associated with Verapamil are:

• Headache
• Constipation
• Increased blood flow to the skin on the face (facial flushing)
• Allergy to active ingredients (hypersensitivity)
• Fatigue
• Ankle swelling
• Nausea and vomiting

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