Sporanox and its Uses
Generic Sporanox belongs to a class of drugs known as the triazoles.
Generic Sporanox is used to treat fungal infections of the toenails and fingernails. It is used to treat some types of fungal infections both internally (inside the body) and externally (skin and nails).
Generic Sporanox can be used in the treatment of a number of different types of fungal infections such as:
|| Top || Working Mechanism of Sporanox
Generic Sporanox is used in the treatment of fungal infections and works by interfering with their growth and repair mechanisms.
Generic Sporanox inhibits the production of a molecule called ergosterol, which is a component of the fungal cell membrane. Damage to this membrane cannot be repaired and this interferes with the cells ability to reproduce.
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Sporanox Dose
Missed Dose of Sporanox
Take the missed dose of Sporanox as soon as you remember. If it is almost time for the next dose, skip the missed dose of Sporanox and take only the next regularly scheduled dose as directed. Do not take a double dose of Sporanox.
Excess Dose of Sporanox
Generic Sporanox in excess dose may show symptoms such as dizziness, ringing in the ears, headache, nausea, vomiting, diarrhea, and abdominal pain.
Conditions for Storage of Sporanox
Store Sporanox at room temperature away from moisture and heat.
Potencies of Sporanox
Sporanox Capsules : Sporanox 100 mg || Top ||
Food and Drug Interactions with Sporanox
- Terfenadine and cisapride are two drugs that must not be taken with Sporanox, since there is the risk of suffering irregular heartbeats.
- Reboxetine (antidepressant) should not be taken with Sporanox.
- The following medications lower the blood levels of Sporanox, making it less effective:
- Rifampicin
- Phenytoin
- Histamine H2 antagonists (e.g. cimetidine, ranitidine)
- Proton pump inhibitors e.g. Prilosec (omeprazole) (treatment of heartburn and stomach ulcers)
- Antacids
- Sporanox may raise blood levels of the following medications. This can cause an increased effect or side effects:
- Rifabutin (used for tuberculosis)
- Repaglinide (used in diabetes)
- Sulphonylureas used for diabetes (e.g. chlorpropamide, glibenclamide, glipizide, tolbutamide)
- Sertindole
- Indinavir (antiviral medication) - avoid use together
- Saquinavir (antiviral)
- Midazolam (sedative)
- Felodipine (used for high blood pressure)
- Digoxin
- Cyclosporin
- Vincristine
- Tacrolimus
- Methylprednisolone
Sporanox may reduce the effectiveness of the oral contraceptive pill.
Sporanox increases blood levels of Simvastatin therefore increasing the risk of muscle breakdown (myopathy).
The effect of blood thinning medications such as nicoumalone and Coumadin (warfarin) may be enhanced and so there is an increased risk of bleeding.
|| Top || Contraindications with Sporanox
Sporanox is contraindicated in pregnancy & Breastfeeding and allergy to any of its ingredients
|| Top || Precautions with Sporanox
Sporanox should be used with caution in:
- Decreased kidney function
- Liver disease
- Numbness and weakness in the extremities, caused by damage to the nerves (peripheral neuropathy)
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Adverse effects with Sporanox
The adverse effects associated with Sporanox are:
- Headache
- Rash
- Abdominal pain
- Disturbances of the gut such as diarrhea, constipation, nausea, vomiting or abdominal pain
- Allergic reaction to active ingredient
- Indigestion (dyspepsia)
- Irregular menstrual cycle
- Disorder of the peripheral nerves causing weakness and numbness (peripheral neuropathy)
- Dizziness
- Nausea and vomiting
- Hair loss (alopecia) with long term use of medication
- Alteration in results of liver function tests
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