Doxycycline and its Uses
Generic Doxycycline is in a class of medications called tetracycline antibiotics.
Generic Doxycycline is used to treat bacterial infections, including pneumonia and other respiratory tract infections; lyme disease; acne; infections of skin, gum disease, genital, and urinary systems; anthrax (after inhalational exposure) and other bacterial infections such as gonorrhea and chlamydia.
Generic Doxycycline is also used to prevent malaria and can also be used to prevent it when visiting high-risk malarial areas, in particular areas where the malaria parasite is resistant to chloroquine.
Generic Doxycycline works by preventing the growth and spread of bacteria.
|| Top || Working Mechanism of Doxycycline
Generic Doxycycline works by preventing bacteria from producing proteins that are essential to them. Without these proteins the bacteria cannot grow, replicate and increase in numbers. Doxycycline therefore stops the spread of the infection and the remaining bacteria eventually die.
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Doxycycline Dose
Missed Dose of Doxycycline
Take the missed dose of Doxycycline as soon as you remember. However, if it is almost time for the next dose of Doxycycline, skip the missed dose and take only the next regularly scheduled dose of Doxycycline. Do not take a double dose of Doxycycline.
Excess Dose of Doxycycline
Generic Doxycycline in excess dose may show symptoms such as nausea, vomiting, and diarrhea.
Conditions for Storage of Generic Doxycycline
Store Generic Doxycycline at room temperature away from moisture and heat.
Potencies of Doxycycline
Doxycycline Tablets Doxycycline 100 mg & Doxycycline 200 mg
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Food and Drug interactions with Doxycycline
- The absorption of doxycycline from the gut may be reduced by the following:
- antacids containing aluminium, magnesium, calcium or bismuth salts (the dose of antacids should be separated from the doxycycline dose by at least two to three hours if they must be used)
- iron preparations
- zinc salts.
- In addition, Generic doxycycline reduces the absorption of iron preparations taken by mouth.
- Dose of Doxycycline may reduce the effectiveness of the combined oral contraceptive pill.
- Doxycycline may increase the anti-blood-clotting effects of anticoagulants such as warfarin. People taking this type of medicine should be monitored when Generic doxycycline is first added to treatment.
- The following medicines may reduce the blood level of doxycycline:
- barbiturates, e.g. phenobarbitone
- carbamazepine
- phenytoin
- Your doctor may need to increase the dose of doxycycline if you are taking these medicines.
- Tetracyclines in general may decrease the effectiveness of penicillin type antibiotics. Doxycycline should be avoided with penicillin.
- Alcoholics may have reduced blood levels of doxycycline. This is because in this group of people alcohol stimulates the liver to metabolize the Generic doxycycline. Alcohol has not been found to have this effect in people who drink moderately.
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Contraindications with Doxycycline
Generic Doxycycline is contraindicated in the following
- Allergy to other tetracycline antibiotics, e.g. doxycycline, minocycline
- Breastfeeding
- Children under 12 years of age
- Pregnancy
- Allergy to one or any of its ingredients
|| Top || Precautions with Doxycycline
Generic Doxycycline should be used with caution in
- Decreased liver function
- Life long inherited blood diseases which can cause a variety of symptoms, including mental health problems (porphyrias)
- Long-term inflammation of skin and some internal organs (systemic lupus erythematosus)
- People taking any medicines with potential to cause adverse effects on the liver
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Adverse effects with Doxycycline
The adverse effects associated with Doxycycline are
- Blood disorders
- Abnormal reaction of the skin to light, usually a rash (photosensitivity)
- Loss of appetite
- Disturbances of liver function
- Inflammation of the food pipe (oesophagitis)
- Difficulty or pain when swallowing (dysphagia)
- Inflammation of the intestines (enterocolitis)
- Mild increase in pressure within the skull (benign intracranial hypertension)
- Hypersensitivity reactions such as swelling of the lips, throat and tongue (angioedema), itchy blistering rash or anaphylactic shock
- Rash
- Diarrhea
- Nausea and vomiting
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